yvaE [2019-07-10 12:05:25]

similar to multidrug-efflux transporter

Locus: BSU33570

Isoelectric point: 8.13

Molecular weight: 12.82 kDa

Protein length: 119 aa

Gene length: 360 bp

Function: unknown

Product: subunit of unidentified multidrug transporter

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Multidrug exporters
• Lifestyles → Coping with stress → Resistance against toxins/ antibiotics/ based on similarity
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,448,693 3,449,052

The protein

Protein family

• paired small multidrug resistance protein family (PSMR family) PubMed
• drug/metabolite transporter (DMT) superfamily (according to UniProt)
• Small multidrug resistance (SMR) (TC 2.A.7.1) family (according to UniProt)

Structure

• 3B5D (from E. coli, 44% identity) PubMed

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yvaF-yvaE-yvaD
  Description: PubMed

Biological materials

Mutant

• MGNA-A502 (yvaE::erm), available at the NBRP B. subtilis, Japan
• BKE33570 (yvaE::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CGCCAAGCATAGAAACACCC, downstream forward: _UP4_GTACATAAAAGCGGGCAGTA
• BKK33570 (yvaE::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CGCCAAGCATAGAAACACCC, downstream forward: _UP4_GTACATAAAAGCGGGCAGTA

References

Reviews

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Original publications

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